PATH’s Center for Vaccine Innovation and Access

Our disease targets

Tackling the toughest disease challenges for underserved populations

Photo: Siri Wood

Photo: Siri Wood

The impact of infectious disease can be devastating in impoverished communities already made vulnerable by malnutrition, underlying and endemic illnesses, crowded and unsanitary living conditions, and seasonal disease patterns exacerbated by climate change. Especially in areas with limited access to healthcare, vaccines offer the best hope for protection by preventing diseases from occurring in the first place. Our disease priorities are guided by the most urgent needs of children and women living in these settings.

Vaccines are the most successful, cost-effective public health intervention available; yet, developing and delivering vaccines against diseases that disproportionately affect people in low-resource countries face unique challenges. All too often, natural market forces are insufficient to drive the development of new, affordable vaccines against many of these diseases. As a result, too many vaccines remain out of reach in the developing world. For some of these diseases, no vaccine exists at all because of lack of investment. Even when vaccines exist and are affordable, making them accessible for everyone can still be difficult when countries lack sturdy policy and delivery frameworks for scale up in routine immunization systems.

To fill these gaps and achieve the greatest impact, our vaccine work targets infectious diseases that are responsible for the highest number of preventable deaths among children and women in low-resource settings.

Explore the pages below to learn about our target diseases, our role in developing and delivering vaccines against them, and select examples of our work.

Additional resources