PATH’s Center for Vaccine Innovation and Access

Supporting country introduction

Improving country readiness and priming for scale

Photo: PATH/Aaron Joel Santos

Photo: PATH/Aaron Joel Santos

PATH is working toward a world where the most vulnerable people are protected from devastating diseases through equitable access to lifesaving vaccines. In order to realize the full potential of new and underutilized vaccines, we work with partners across the vaccine development and delivery spectrum to create an enabling environment for vaccine button-cvia-read-about-our-workintroduction and address the complex factors that influence vaccine acceptance and use in low-resource countries. We partner with countries at every stage to help introduce and sustain vaccination programs for those most in need and in some of the world’s most challenging settings.

Optimizing vaccine development and delivery for country needs

Before a country can introduce a vaccine there are many elements to consider such as dosing schedules, financing mechanisms, and supply chain needs. Even during vaccine development stages, we partner closely with immunization program managers and ministries of health in low-resource countries so that their needs inform every phase of development, planning, and delivery. Through these partnerships, we help ensure that when a vaccine comes to market, countries that need it are ready to receive it.

Currently, we provide technical assistance to national immunization programs on planning, preparing, and implementing vaccine introductions for a variety of diseases including human papillomavirus (HPV), Japanese encephalitis, and rotavirus.

Generating data for decision-making

PATH collaborates with national governments and other key partners such as the World Health Organization and UNICEF to establish sustainable systems for diagnosing and tracking disease incidence and to model the cost effectiveness of introducing specific vaccines. We also support and conduct pivotal clinical trials to inform the optimal performance of vaccines and lead operations research to determine effective delivery strategies. These activities generate key data to provide global and country policymakers with the information needed to make decisions about vaccine introduction and program implementation.

Additionally, we help mobilize community acceptance and generate demand and political will in support of accelerating new vaccine introduction and vaccine implementation. 

PATH IN ACTION

Working toward cervical cancer elimination

Girl receiving HPV immunization, Nyamiyaga Primary School, IbandaPATH has played a critical role in efforts to build the evidence base for appropriate cervical cancer interventions and provide technical assistance to low-resource countries committed to cervical cancer prevention. We currently provide technical assistance to more than 26 countries around the world for the planning, implementation, and evaluation of HPV vaccination programs. We support country HPV vaccine introductions through demonstration programs and national introductions. This work is part of a larger initiative to introduce HPV vaccines in low- and middle-income countries while strengthening the availability of screening and treatment alternatives. Since HPV vaccines first became available in 2006, more than 70 countries and territories have introduced HPV vaccines into their national immunization programs. [Photo: PATH/Robin Biellik]

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