HIV/AIDS and Tuberculosis Global Program

Our featured projects

The mission of PATH’s HIV/AIDS and Tuberculosis (TB) Global Program is to support universal access to, and strengthen the evidence base for, effective HIV/AIDS and TB prevention, diagnosis, care, and treatment. Our projects emphasize collaboration, innovation, local capacity development, and evidence-based approaches to improve health outcomes.

Our cross-cutting technical expertise includes:

  • Strengthening health systems by training health care providers, improving labs, and linking communities to health systems.
  • Monitoring and evaluation and implementation science, such as:
    • Addressing gender dynamics and stigma in programming, research, and evaluation.
    • Developing innovative databases to track large projects.
    • Conducting program evaluations.
    • Performing feasibility and accessibility studies.
  • Designing, implementing, and evaluating behavior change communication/advocacy, communication, and social mobilization activities.

PATH has worked with a broad range of funders and partners in countries such as Ukraine, India, Thailand, Cambodia, Vietnam, Mexico, Tanzania, Senegal, the Democratic Republic of Congo, Ethiopia, Uganda, Zambia, South Africa, and Zimbabwe. Read on for highlights of our recent work.

Integrated HIV/AIDS Project in the Democratic Republic of Congo (ProVIC)

Congolese march with a Champion Community sign

Members of a Champion Community in Kinshasa celebrate their achievements during a festival. Photo: Salva Mulongo.

In the Democratic Republic of Congo (DRC), only a small fraction of the country’s nearly 71 million people have ever been tested for HIV, and most who test positive do not have access to the care, support, and treatment they need. Under ProVIC, PATH leads a consortium of partners working to build the capacity of individuals, families, communities, and institutions in five provinces to mobilize and sustain action against the disease. At the heart of ProVIC’s implementation strategy is the Champion Community approach, through which more than a million individuals have been reached to date. ProVIC is the US President’s Emergency Plan for AIDS Relief’s (PEPFAR’s) flagship HIV/AIDS project and the largest community-based HIV/AIDS project in the DRC. Learn more.

TB Indefinite Quantity Contract (IQC) Task Order 01

Two TB patients take medicine.

Two TB patients receive a course of treatment. Photo: PATH.

TB is one of the greatest killers worldwide and the leading cause of death among people infected with HIV. Building on our successful work with three previous task orders under the USAID Technical Assistance Support Contract, PATH is currently leading a five-year, follow-on TB IQC task order. This multi-country portfolio includes a consortium of organizations that provide technical support at the community, district, and national levels to implement a comprehensive package of interventions in line with the international Stop TB Strategy. Learn more.

Arise: Enhancing HIV Prevention Programs for At-Risk Populations

Poster that says "informed, responsible, alive."

A community outreach poster promotes HIV couples testing in Zambia under Arise. Image: Zambia-Emory HIV Research Project.

With funding from the Canadian International Development Agency, PATH is providing technical and financial support to HIV prevention projects that target most-at-risk populations such as HIV-positive pregnant women, sero-discordant couples, injecting drug users, and female sex workers. Our goal is to reach nearly 100,000 people in sub-Saharan Africa and India, rigorously tracking our results along the way using operations research, and including key outcomes like HIV incidence to understand and evaluate impact. Importantly, each project must implement services at a cost of less than $500 per infection averted—to help us better understand the types of prevention approaches that most cost-effectively avert infections among men, women, and children who are most at risk. Learn more.

Impact Evaluation of Tostan’s Community Empowerment Program in Senegal

Two women from Tostan hold a baby.

PATH’s work addresses inequitable gender norms and how they can lead to increased risk of HIV, particularly for women and girls. Photo: PATH.

Evidence continues to highlight the critical role and impact of gender inequity on health outcomes. With longstanding expertise in addressing these links, PATH is conducting rigorous monitoring and evaluation to identify and support effective approaches for transforming inequitable gender norms and preventing gender-based violence—both of which can fuel HIV transmission. In Senegal, we’re leading an evaluation of a community-based health and human rights awareness and education program implemented by Tostan, our partner organization. Learn more.

Additional resources

Meeting the global challenge of HIV/AIDS