Sayana Press Introduction and Research: Expanding Access and Options
About the product
Sayana® Press is a three-month, progestin-only, all-in-one injectable contraceptive that combines the drug and needle in the Uniject™ injection system. Sayana Press is small, light, easy to use, and requires minimal training, making it especially suitable for community-based distribution—and for women to administer themselves through self-injection. Sayana Press can improve access to a safe and effective contraceptive option, and increase women’s autonomy.
Self-injection with Sayana Press
Self-injection of Sayana Press was officially approved by the United Kingdom’s lead stringent regulatory authority in 2015, and has been recommended by WHO in contexts where women have information, training, and support. Through 2017, PATH is conducting research on self-injection of Sayana Press in collaboration with ministries of health in Senegal and Uganda, and learning how to support women in these settings to self-inject safely and effectively.
Product introduction: Making injections available from new providers
Sayana Press has been available from providers in Senegal, Uganda, Burkina Faso, and Niger since 2014, under a country-led introduction initiative coordinated by PATH. These introductions have helped to make injectable contraception available in remote locations, closer to where women live. Between June 2014 and September 2015, more than 230,000 doses of Sayana Press were administered by family planning providers in the four countries. To understand the potential impact of Sayana Press administered by providers, PATH and partners are also conducting studies on the effectiveness and cost-effectiveness of Sayana Press administered by clinic-based (Burkina Faso) and community-based (Uganda) health providers; results are anticipated in 2017.
Pricing and regulatory approval of Sayana Press
Under a novel pricing agreement negotiated by Pfizer Inc., the Bill & Melinda Gates Foundation, and the Children’s Investment Fund Foundation (CIFF) in 2014, qualified purchasers in the world’s poorest 69 countries can obtain Sayana Press for US$1 per dose. For more information on this topic, please contact firstname.lastname@example.org.
Sayana Press has regulatory approval in the European Union and more than 25 countries around the world.† The formulation of DMPA used in Sayana Press is also approved in the United States.
PATH Sayana Press key fact sheets
- Sayana Press: Product and Project Summary
- Monitoring Sayana Press Pilot Introduction
- Sayana Press Self-Injection Research
- Frequently Asked Questions About Sayana Press
- Sayana Press Clinical Brief
- L’Introduction Pilote de Sayana Press: Résumé de Projet
- Suivi de L’introduction Pilote de Sayana Press
- Recherche sur l’auto‐injection de Sayana Press
- Questions Fréquentes Concernant Sayana Press
- Sayana Press Dossier Clinique
- January 2016 self-injection newsletter
- October 2015 pilot introduction newsletter
- July 2015 self-injection newsletter
- April 2015 pilot introduction newsletter
- Janvier 2016 bulletin auto-administration
- Octobre 2015 bulletin introduction pilote
- Julliet 2015 bulletin auto-administration
- Avril 2015 bulletin introduction pilote
PATH blog posts and features about Sayana Press
- A condom for women, a diaphragm, and an all-in-one injectable contraceptive (2015)
- An implementer’s perspective on family planning as a human right (2015)
- Empowering women one page at a time (2015)
- PATH 2014 Annual Report “A Beautiful Choice” Sayana Press feature and video (2014)
- A novel contraceptive makes life easier in Uganda and beyond (2014)
- How the right contraceptive can change a woman’s life (2014)
- Putting family planning within reach (2013)
PATH announcements about Sayana Press
- PATH welcomes groundbreaking regulatory approval for contraceptive self-injection (2015)
- PATH welcomes news that millions more women can access Sayana Press (2014)
- Injectable contraceptive launched in Burkina Faso to expand choice and address unmet need (2014)
Sayana Press and Depo-Provera are registered trademarks of Pfizer Inc. Uniject is a trademark of BD.
†Sayana Press was approved in the European Union via procedure number UK/H/0960/002UK/H/0960/002. The UK was the Reference Member State. A Public Assessment Report is available at the Heads of Medicines Agency website and the Medicines and Healthcare Products Regulatory Agency web page.